An fi danganta koko dacakulankuma yana da fa'idodin sinadirai iri-iri waɗanda zasu iya tabbatar da ingantaccen halayen lafiya.Waken koko shine tushen haɗari na polyphenols na abinci, wanda ya ƙunshi ƙarin antioxidants na ƙarshe fiye da yawancin abinci.Sanannen abu ne cewa polyphenols suna da alaƙa da tasirin kiwon lafiya masu fa'ida, don haka koko yana da wadata a cikin polyphenols, da cakulan duhu, wanda ke ƙunshe da kaso mai yawa na cacao da mahadi masu yawa na antioxidants dangane da sauran nau'ikan cakulan, sun ɗauki mahimmancin mahimmanci ga lafiya.

Abubuwan sinadirai na koko

Cocoa yana ƙunshe da adadi mai yawa na mai, ~ 40 -50% yana cikin man shanu.Wannan ya ƙunshi 33% oleic acid, 25% palmitic acid, da 33% stearic acid.Abubuwan da ke cikin polyphenol ya ƙunshi kusan kashi 10% na busasshen nauyin wake.Polyphenols da koko ya ƙunshi sun haɗa da catechins (37%), anthocyanidins (4%), da proanthocyanins (58%).Proanthocyanins sune mafi yawan phytonutrients a cikin koko.

Yana da mahimmanci a lura cewa dacin polyphenols shine dalilin da cewa wake na koko ba shi da kyau;masana'antun sun haɓaka dabarun sarrafawa don kawar da wannan ɗaci.Duk da haka, wannan tsari yana rage yawan abubuwan da ke cikin polyphenol.Ana iya saukar da abun cikin polyphenol har zuwa ninki goma.

Har ila yau, wake na koko ya ƙunshi mahadi na nitrogen - waɗannan sun haɗa da furotin da methylxanthines, wato theobromine da caffeine.Cocoa kuma yana da wadata a cikin ma'adanai, phosphorus, iron, potassium, jan karfe, da magnesium.

Illolin zuciya da jijiyoyin jini na shan koko

An fi samun koko a cikin nau'in cakulan;Amfani da cakulan ya ga karuwa kwanan nan a duniya, tare da cakulan duhu ya zama sananne saboda yawan kokon da yake da shi da kuma tasirin lafiyar lafiya idan aka kwatanta da al'ada ko cakulan madara.Bugu da kari, zo a kan cakulan tare da ƙananan abun ciki koko irin su cakulan madara yawanci suna da alaƙa da abubuwan da ba su dace ba saboda yawan sukari da abubuwan mai.

Dangane da shan koko, cakulan duhu shine babban kayan abinci na koko mai alaƙa da tasirin inganta lafiya;koko a danyen sigarsa ba ta da dadi.

Akwai jerin tasiri masu amfani akan tsarin zuciya da jijiyoyin jini wanda ke da alaƙa da cin abinci na yau da kullun na koko da abubuwan sha waɗanda ke tattare da tasirin hawan jini, jijiyoyin jini da aikin platelet, da juriya na insulin.

Polyphenols, waɗanda ke cikin babban taro a cikin koko da cakulan duhu, na iya kunna endothelial nitrogen oxide synthase.Wannan yana haifar da samar da nitrogen oxide, wanda ke rage karfin jini ta hanyar inganta vasodilation.Nazarin ya nuna haɓakawa a cikin saurin bugun bugun jini da ƙididdigar maki sclerotic.Haka kuma, mafi yawan adadin epicatechins na plasma yana taimakawa a cikin sakin vasodilator da aka samu na endothelium kuma yana haɓaka haɓakar procyanidins na plasma.Wannan yana haifar da haɓakar haɓakar nitrogen oxide, da kasancewarsa.

Da zarar an sake shi, nitrogen oxide kuma yana kunna hanyar haɗin prostacyclin, wanda kuma yana aiki azaman vasodilator kuma haka ma yana ba da gudummawar kariya daga thrombosis.

Wani nazari na tsarin ya nuna cewa amfani da cakulan na yau da kullum, wanda aka ƙididdige shi a matsayin <100g / mako, na iya danganta shi da rage haɗarin cututtukan zuciya;Mafi dacewa kashi na cakulan shine 45g / mako, kamar yadda a mafi girman matakan amfani, ana iya magance waɗannan tasirin kiwon lafiya ta hanyar yawan amfani da sukari.

Dangane da takamaiman nau'ikan cututtukan cututtukan zuciya, wani bincike mai yiwuwa na Sweden ya danganta amfani da cakulan tare da rage haɗarin infarction na zuciya da cututtukan zuciya na ischemic.Duk da haka, an ba da rahoton rashin haɗin kai tsakanin shan cakulan da kuma hadarin ciwon fibrillation a cikin ƙungiyar likitocin maza na Amurka.Tare da wannan, nazarin yawan jama'a na mahalarta 20,192 ya kasa nuna haɗin kai tsakanin yawan shan cakulan (har zuwa 100 g / rana) da kuma raunin zuciya.

An kuma nuna Cocoa yana taka rawa wajen magance matsalolin kwakwalwa kamar bugun jini;Babban Jafananci, tushen yawan jama'a, binciken da ake tsammanin ya ƙididdige ƙungiyar tsakanin rage haɗarin bugun jini a cikin mata, amma ba maza ba, dangane da shan cakulan.

Tasirin amfani da koko akan glucose homeostasis

Cocoa ya ƙunshi flavanols wanda ke inganta glucose homeostasis.Za su iya rage jinkirin narkewar carbohydrate da sha a cikin hanji, wanda ke samar da tushen aikin su.An nuna abubuwan da aka cire na koko da procyanidins don dogaro da kashi-kashi don hana pancreatic α-amylase, pancreatic lipase, da ɓoye phospholipase A2.

Cocoa da flavanols kuma sun inganta rashin fahimtar glucose ta hanyar daidaita jigilar glucose da sunadaran siginar insulin a cikin kyallen jikin insulin kamar hanta, adipose tissue, da tsokar kwarangwal.Wannan yana hana lalacewar oxidative da kumburi mai alaƙa da nau'in ciwon sukari na 2.

Sakamako daga Nazarin Kiwon Lafiyar Likitoci kuma sun ba da rahoton wata alaƙar da ba ta dace ba tsakanin shan koko da abin da ya faru na ciwon sukari.A cikin rukuni na batutuwa masu yawa, an sami raguwar haɗarin haɓaka nau'in ciwon sukari na 2, tare da mafi yawan samfuran cakulan da flavonoids da aka samu na koko.

Bugu da ƙari, wani bincike mai yiwuwa a cikin mata masu juna biyu na Japan ya kuma nuna raguwar haɗarin ciwon sukari na ciki a tsakanin waɗannan matan da ke cikin mafi yawan adadin cakulan.

Sauran nazarin da ke nuna haɗin gwiwar koko da glucose homeostasis sun nuna cewa ƙwayar koko da kuma procyanidins sun hana samar da enzymes don narkewar carbohydrates da lipids, wanda ke nuna rawar da ake ciki a cikin sarrafa nauyin jiki tare da rage cin abinci mai kalori. .

Bugu da ƙari, makafi guda ɗaya, bazuwar nazarin ɗan adam mai sarrafa wuribo-sarrafawa ya nuna fa'idodin rayuwa na cinye cakulan duhu mai wadataccen polyphenol da yiwuwar mummunan tasirin da ke faruwa tare da cakulan-malauci na polyphenol.

Tasirin shan koko akan ciwon daji

Amfanin koko mai inganci akan kansa yana da cece-kuce.Tun da farko binciken ya nuna cewa shan cakulan na iya zama abin da zai iya haifar da ci gaban ciwon daji da kuma ciwon nono.Sai dai wasu bincike sun nuna cewa koko na iya hana ci gaban kwayoyin cutar kansain vitro;duk da haka, ba a fahimci hanyoyin yin wannan aikin rigakafin cutar kansa da kyau ba.

Dangane da bangaren da ke cikin koko wanda ke samar da irin wannan tasirin anti-cancer, an nuna procyanidins musamman don rage yawan kamuwa da cutar kansar huhu da kuma rage girman adenoma thyroid a cikin berayen maza.Wadannan mahadi kuma na iya hana mammary da pancreatic tumorigenesis a cikin berayen mata.Cocoa procyanidins kuma yana rage ayyukan da ke da alaƙa da ayyukan da ke da alaƙa da ƙari irin su ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta da kuma aikin angiogenic.

Maganin nau'ikan nau'ikan nau'ikan kwayar cutar daji na ovarian tare da nau'ikan nau'ikan koko mai wadata a cikin procyanidin an nuna su haifar da cytotoxicity da chemosensitization.Musamman ma, adadi mai mahimmanci na sel a cikin G0/G1 lokaci na zagayowar tantanin halitta tare da ƙara maida hankali.Baya ga wannan, an kuma kama wani adadi mai yawa na sel a cikin lokacin S.Ana tsammanin waɗannan tasirin ana danganta su da haɓaka matakan intracellular na nau'in iskar oxygen mai amsawa.

Yawancin bincike sun kuma nuna tasirin koko akan haɗari da yaduwar cutar kansa.An nuna polyphenols na koko don samar da tasirin antiproliferative saboda tsangwama tare da polyamine metabolism a cikinin vitrokaratun ɗan adam.A cikiin vivoNazarin bera proanthocyanidins da ke cikin cakulan duhu an nuna su don hana mutagenicity na ciwon daji na pancreatic a matakin farawa da kuma yin tasirin chemoprotective a cikin huhu, yana rage abin da ya faru da yaduwar carcinomas ta hanyar dogaro da kashi.

Don sanin cikakken tasirin koko akan haɗarin rage haɗari ko tsananin cutar kansa, ƙarin fassarar da binciken da ke gaba ya zama dole.

Tasirin koko akan tsarin rigakafi

Nazarin kan tasirin tsarin rigakafi da ke da alaƙa da koko ko cakulan amfani da koko ya nuna cewa cin abinci mai wadatar koko zai iya daidaita martanin rigakafi na hanji a cikin ƙananan beraye.Musamman ma, an nuna theobromine da koko suna da alhakin ƙaddamar da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta.

A cikin nazarin ɗan adam, binciken da aka yi da makafi biyu na makafi ya nuna cewa amfani da cakulan duhu ya inganta abubuwan mannewa na leukocyte da kuma aikin jijiyoyin jini a cikin maza masu kiba.Bugu da ƙari, mahalarta a cikin sashin layi, dubawa, nazarin ɗan adam waɗanda ke cinye koko mai matsakaicin matsakaici an gano cewa sun sami raguwar yawan cututtukan da ke faruwa idan aka kwatanta da ƙananan masu amfani.Bugu da ƙari, cin koko yana da alaƙa da rashin lafiyar jiki da kuma motsa jiki.

Tasirin koko akan nauyin jiki

A cikin ƙima, akwai haɗin gwiwa tsakanin amfani da koko da yuwuwar rawarsa a matsayin ma'aunin warkewa daga kiba da ciwo na rayuwa.Wannan ya zo daga da yawain vitronazarin beraye da bera da kuma gwaje-gwajen sarrafa bazuwar, ɗan adam mai yiwuwa, da nazarin sarrafa shari'a a cikin mutane.

A cikin beraye da berayen, rodents masu kiba da aka haɗa da koko sun rage haɗarin kumburi da ke da alaƙa da kiba, cutar hanta mai kitse, da juriya na insulin.Hakanan shan koko yana rage haɓakar fatty acid da jigilar hanta da kyallen jikin adipose.

A cikin mutane, wari ko cin cakulan duhu na iya canza yunwa, yana hana ci saboda canje-canje a cikin ghrelin, hormone da ke da alhakin jin yunwa.Yin amfani da cakulan duhu akai-akai zai iya tasiri ga matakan lipoprotein cholesterol mai yawa ("mai kyau" cholesterol), rabon lipoproteins, da alamun kumburi;Ana ganin irin wannan tasirin lokacin da aka nuna amfani da cakulan duhu a hade tare da almonds, don inganta bayanan martaba na lipid a cikin jini.

Gabaɗaya, koko da samfuran da aka samu suna iya aiki azaman abinci mai aiki kamar yadda suke ɗauke da mahadi da yawa waɗanda ke samar da fa'idodin kiwon lafiya.Kyakkyawan fa'idar lafiyar sa yana shafar tsarin rigakafi, cututtukan zuciya, da tsarin rayuwa don suna kaɗan.Bugu da ƙari, nazarin ya nuna tasiri mai kyau na amfani da koko akan tsarin kulawa na tsakiya.

Akwai wasu iyakoki tare da nazarin da aka tsara don bincika tasirin koko - wato, suna kimanta abubuwan da ke inganta lafiyar koko ba na cakulan kanta ba.Wannan abu ne sananne yayin da aka fi cin koko a cikin nau'in cakulan, wanda yanayin abincinsa ya bambanta da na koko.Don haka, rawar da cakulan kan lafiyar ɗan adam bai yi kama da na koko ba.

Sauran iyakoki sun haɗa da ƙarancin ƙarancin binciken cututtukan cututtukan da ke yin nazarin tasirin lafiyar koko a cikin nau'i daban-daban - wato cakulan duhu wanda ke ƙaruwa cikin shahara.Bugu da ƙari, akwai abubuwa da yawa masu ruɗarwa kamar sauran abubuwan abinci, abubuwan da ke tattare da muhalli, salon rayuwa, da ƙarar shan cakulan, da kuma abubuwan da ke tattare da shi waɗanda ke iyakance ƙarfin shaidar da binciken ya gabatar.

Ƙarin karatun fassarar ya zama dole don tantance yiwuwar tasirin shan koko, da cakulan da kuma tabbatar da sakamakon da aka nuna a cikin gwaje-gwajen in vitro akan dabbobi.